Euginius

Euginius Help Document

last update: May 23, 2012

Contents

GMO selection

List with GMOs and their identifiers

List with GMOs and traits

List with GMOs and genetic elements

Method search

Detection method search

Method verification search

Reference material search

GMO authorisation search

Search for generic approval category

Search for EU application details (intended uses and their legal status)

Search for literature with content-type "safety"

GMO analysis tool

Search for GMO or literature using free text

Free-text search for GMOs

Free-text search for literature

Advanced GMO search

Advanced literature search

Data entry tool

Related Methods

Rikilt

BVL


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Euginius Help text


GMO selection

Within the GMO tab, there are different ways to find information on a specific GMO. A GMO can be accessed: Furthermore, this site provides a free-text search field.
This can be used with any of the identifiers mentioned above or with other information of a specific GMO. Use * as wildcard, if necessary.
see Free-text search for GMOs for more instructions.

GMOs are sorted by default on their name (boxed arrows). Boxed arrows above column indicate that the list can be sorted on this column as well..
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List with GMOs and their identifiers

This page shows a list of all GMOs in this database. You can view and sort GMOs by their identifiers.
These identifiers are:

Go to GMO authorisation search for more information about the EU authorisation status (i.e. approved, approved with restrictions or phasing out or not approved in the EU).


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List with GMOs and traits

This view provides a table with GMOs and their traits, that can be filtered according to principles of trait classification.
You can obtain al list of GMO registered in this database based upon their specific traits.
This list can be sorted on GMO name or Trait.
Use "Define Filter Criteria" to select specific traits from the thesaurus and add them to the filter criteria.
You can add traits from different levels in the tree. Adding a high level trait will also select GMOs with traits below that "parent" trait.
For example, selecting Virus resistance will also list a GMO with trait Potato leaf roll virus resistance:

For a complete look of the thesaurus download the Trait_thesaurus.pdf.
This thesaurus is also available in OboEdit format. Please contact the database manager for details..


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List with GMOs and genetic elements

You can obtain al list of GMO registered in this database based upon the genetic elements known or expected to exists in this GMO. Use "Define Filter Criteria" to select specific elements from the thesaurus and add them to the filter criteria.
You can add genetic elements from different levels in the tree. Adding a high level element will also select GMOs with elements below that "parent" trait.
For example, selecting CS-cry will also list a GMO with traits CS-cry1Ab and CS-cry3A:

For a complete look of the thesaurus download the DNAelement_thesaurus.pdf.
This thesaurus is also available in OboEdit format. Please contact the database manager for details..

GMOs can be filtered by selecting genetic elements that are added to the search criteria.
When applying this filter option, only the selected elements will be shown.
By pressing the show function in the result table column Genetic Elements, all selected elements are shown.
Pressing hide returns to displaying the selected elements only.
Stacked events can be excluded by selecting the radio button.


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Method search

There are two ways to look for and to display methods:

Detection method search

PCR detection methods are searchable by pre-selecting a set of methods and by using filter criteria.

Searchable method sets are:

By entering specific filter criteria, the user can restrict the search in the following way:

Method verification search

This search tool can be used to create a table showing the specificity data of a selected set of PCR methods and thereby their ability to detect GMOs. The specificity data for the methods are either verified experimentally using reference materials or theoretically (in silico) according to available information (publication, plasmid map or sequence).

Searchable method sets are:

By entering specific filter criteria, the user can restrict the search in the following way:

Method verification search result

The output of the search is a list tabulating the selected set of methods (targets) and the verification value of each method for a specific GMO. The levels of verified specificity of the method for each GMO are indicated by numbers: A value in a
green box
indicates that the GMO should be detectable by the method according to the verification data (target present / detected).
The minus (-) value indicates that the GMO is not detected by the method according to the verification (target not present / not detected). The value -1 indicates that the specificity is unknown.
The show/hide functionality allows to see all verification values (default is >0).

Reference material search

Reference material is searchable on different criteria. When only certified material should be displayed check the radio button.
Default sorting is on Description (boxed arrows). This is the description of the material according to supplier's labelling.
extra comment refers to a relevant extra comment inside the marked file.


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GMO authorisation search

In this database the authorisation status of a GMO can be consulted in two ways:

Search for generic approval category

Information regarding the use of the GMO in food, feed, for cultivation or other uses can be found when searching for generic approval category.
The authorisation status of a GMO can be consulted using filter criteria to limit the list of GMOs. The four icons refer to: The traffic light colours refer to: In the EU due to complex legal conditions, the categories may be further specified. However, these conditions are not applicable for decisions outside the EU

Search for EU application details (intended uses and their legal status)

The authorisation status of a GMO can be consulted using filter criteria to limit the list of GMOs. In the EU, due to complex legal conditions, the categories may be further specified. However, these conditions are not applicable for decisions outside the EU.


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Search for literature with content-type "safety"

Literature describing the specific safety aspects of GMOs or elements can be consulted by searching on GMO name, element name or DNA name. In the output, default sorting is on Publication year (boxed arrows). The literature can be available as document (pdf) and/or as hyperlink (URL). The date in the pdf name refers to the date that the pdf was uploaded to EUGINIUS. Other literature is available at the menu item Search.


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GMO analysis tool

Managing the result table: Explanation of icons and colors in result table:


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Search for GMO or literature using free text

Free text keyword search on different items. Use * as wildcard if necessary. Results will initially be ranked on relevancy.
Also search options for authorisation, methods and reference material using controlled vocabularies are available.

Free-text search for GMOs

The term entered into the text field will be used as search criterion for a number of fields in the database.
The search is case-insensitive and * can be used as wildcard.
Fields used for the search are:

The result will be a table with GMOs. The function advanced search is available to restrict the result list.

Strategy and examples

search term(s) will find GMOs with
Bt* names "Bt11", "Bt10 maize", "BT10 potato", "FR-Bt1", etc.
BTØ11 and BTO11 names "Bt11", "Bt10 maize"
305423 with UID "DP-3Ø5423-1"
MON 00810 6 UID "MON-ØØ81Ø-6"
4/11/15/16 name "4, 11, 15, 16 "
RRS alias "RRS" (=GTS 40-3-2)
zea species "Zea mays"
soybean species "Glycine max"
syngenta UID "Syngenta Seeds, Inc"
yieldgard tradename "YieldGard VT PRO", "Yieldgard™", "Maxguard/Yieldgard", etc.
bt11 name "Bt11" and tradename "unapproved Bt11"
insect trait "Insect resistance"

Free-text search for literature

The term entered into the text field will be used as search criterion for a number of fields in the database.
The search is case-insensitive and * can be used as wildcard.
Fields used for the search are:

The result will be a table with publications, including the fields Citation, Publication year, Publishing authority, Publication type, Content types, Relevance. The content of the field Citation is a hyperlink to more details about the publication.

Strategy and examples

search term(s) will find publications with
broiler "broiler" in abstract (e.g. a scientific opinion from EFSA).
environmental safety "environmental safety" in citation (e.g. a website from CFIA).
kanamycin "kanamycin" in keywords (e.g. a scientific opinion from EFSA).

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Advanced GMO search

In " Advanced GMO search" you can select predefined criteria for your search.
It is possible to select one or more values from a list and combine them to one query.

The result will be a list of GMOs and stacks with their identifiers. Go to List with GMOs and their identifiers for more information.

The result list can be refined using the hyperlink "Refine selection" above the result table. This will enable you to add more (or remove) criteria.


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Advanced literature search

In " Advanced literature search" you can select predefined criteria for your search.
It is possible to select one or more values from a list and combine them to one query.

The result will be a list of GMOs and stacks with their identifiers. Go to List with GMOs and their identifiers for more information.

The result list can be refined using the hyperlink "Refine selection" above the result table. This will enable you to add more (or remove) criteria.


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Data entry tool

The Data Entry tool is only availble to the partners.


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Related methods

This method is/these methods are related to the method shown.
For example, method QT-EVE-ZM-005 METHODE is related to QT-TAX-ZM-002 because QT-TAX-ZM-002 detects the species in combination with this event specific method.
The ration between them is used for quantification of the amount of GMOs in the sample.
This has been recommended by JRC.


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RIKILT

RIKILT - Institute of Food Safety, part of Wageningen University and Research center (Wageningen, NL) is an independent research institute in the area of the safety and wholesomeness of food. RIKILT performs advanced research with relation to the detection, identification, functionality and effects of compounds in feed and plant- and animal-based food products.
RIKILT supports national and international governments with laboratory activities in cases of food or feed incidents and crises with advice relating to the establishment of norms and methods of analyses and the approval of food and feed ingredients of plant and animal origin. RIKILT participates in many different national and international scientific (advisory) platforms and centres of expertise. RIKILT is designated as the Dutch National Reference Laboratory (NRL) for GMO detection in both food and feed. Activities are carried out in close collaboration with European Network of GMO Laboratories (ENGL).

RIKILT is accredited under ISO 17025 to perform 53 methods for GMO detection, identification and quantification and this number is increasing continuously. These methods include GMO event-, construct- and element-specific methods. In addition, RIKILT develops multimethods on the basis of advanced PCR and sequence analysis strategies, including NGS (next generation sequencing).
Website: www.rikilt.wur.nl .


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BVL

The Federal Office of Consumer Protection and Food Safety (BVL) is the central German Federal institution in the area of food safety. It is responsible for the authorisation of plant protection products, veterinary drugs and genetically modified organisms (GMO). It is the National GMO Reference Laboratory. Since the foundation in 2002, the aim of the BVL has been to improve the coordination between the Federal Government and the Federal States, to improve risk communication and to manage risks before they turn into crises
Website: www.bvl.bund.de